Tokyo's shopping and culture vultures can get their fix in one place when the Mori Art Museum is unveiled October 18. Part of the hyper trendy Roppongi Hills complex—a new $2.5 billion multi-purpose development where the likes of Louis Vuitton, Issey Miyake, and Christian Lacroix have already planted their registers—the Richard Gluckman-designed museum occupies the top two floors of a 54-story tower. Its namesake, real estate magnate Minoru Mori (who is also artist Mariko Mori's uncle), has managed to get New York's MoMA to lend works on an ongoing basis. Between that and the shopping, we can't imagine a better title for the inaugural exhibition than Happiness: A Survival Guide for Art and Life.

After its peep show-themed Jeremy Scott extravaganza during Fashion Week, Manhattan's Deitch Projects is hosting an exhibition of work by New York artist Ryan McGinness. Along with paintings and a large-scale mural, it features a human-size maze which McGinness—who is one of the wittier blurrers of the line between graphic design and art—has covered with circular mirrors and the graphic iconography for which he's known. McGinness's images are an ironic blend of Pop and retrofuturist kitsch (he first received attention for his 1999 book "Flatnessisgod"), but here he seems to be evolving into a more fantasy-oriented formula in which symbols, organic forms and patterns are more layered and dense. Another, simultaneous exhibition called Project Rainbow at the 222 gallery in Philadelphia coincides with his new book of the same name.

Those in London will want to head to the south end of Regents Park and check out the Frieze Art Fair. Organized by the people behind the magazine of the same name, this inaugural installation of the world's latest art gathering will focus on art-world mainstays such as Cindy Sherman, Peter Saul and Barry McGee (left), as well as newer darlings, including Markus Draper and Won Ju Lim. Over 120 exhibitors are joining in—alongside lectures and artists' special projects—in a temporary structure designed by up-and-coming architect David Adjaye.

There's something warm and fuzzy about seeing a big name artist in a little space. And that's the case with Gary Hume's current show at Matthew Marks's diminutive new one-room gallery (which joins two not-so-little Marks spaces already in Chelsea). Here, the British painter, a master of color and organic, abstract representation whose also put his mark on Stella McCartney frocks, is showing just three paintings in a more somber palette and six smaller versions of his earlier, monochromatic Back of a Snowman sculpture.